This method, initially employed by Dr. Pistor in France in 1952 for rheumatic diseases, later extended to aesthetic purposes, has become one of the widely practiced methods globally today.


It’s used as a supportive method for procedures such as liposuction, facelifts, facial rejuvenation, and hair transplants in appropriately selected cases.


By injecting certain vitamins and similar products into the mesoderm (the middle layer of the skin) using very fine needles, fat cells in the area initiate their own fat burning, akin to the process during weight loss. These products also aid in improving circulation in the area, effectively addressing cellulite, known as the ‘orange peel’ appearance.

Areas of Mesotherapy Application

Skin Rejuvenation: This treatment, performed with hyaluronic acid multivitamin complexes, is one of the effective methods to restore sagging skin due to reduced collagen synthesis from aging and the adverse effects of the sun. Injecting vital vitamins and antioxidants into the skin’s subdermal layers with short, fine needles increases collagen synthesis and enhances skin moisture levels, resulting in its rejuvenation. This approach helps achieve a firm and radiant skin appearance.




It notably enhances results when used as a support to procedures like facelifts, Botox, fillers, and chemical peels.


Cellulite Treatment: Applied in 8-10 sessions, once a week. In advanced stages of cellulite, increasing the number of sessions may be necessary. Mesotherapy’s effects on cellulite include:


  • Increased regional blood and lymphatic circulation.
  • Encouragement of fat deposits breakdown, leading to increased fat release.
  • Causing the rupture of firm fibrous connections responsible for the ‘orange peel’ appearance.
  • Augmenting lymphatic drainage.
  • Increased effectiveness when combined with vacuum-radiofrequency treatments.
  • Reducing the likelihood of recurrence by maintaining a healthy diet and incorporating daily walks.


Hair Loss: It doesn’t have an impact on male pattern or androgenic hair loss. For these types of hair loss, hair transplantation or supporting hair transplants is recommended. However, hair mesotherapy proves beneficial for women experiencing hair loss. It’s commonly applied in sessions during intense hair loss periods after childbirth or seasonal hair loss.


During intense hair loss periods, hair mesotherapy is suggested once a week initially, followed by monthly sessions.


Localized Fat Accumulation: It can be applied to inner and outer thigh fat, waist and abdominal fat, back under the bra line, and above the knees. It may require up to 10 sessions, once a week. Typically, it’s administered in 8-10 sessions with a one-week interval.